endothelium of heart

Endothelia are considered the “brains” of blood vessels. Endothelium is a specialized type of epithelium found in the lining of blood and lymphatic vessels. However, research over the last 25 years has shown that the endothelium is an active, multi-functional organ that plays a vital role in metabolic, immunologic, and cardiovascular health. Because it is adjacent to the bloodstream, the endothelium can signal a blood vessel’s muscle to respond to changes in pressure and inflammation. As mentioned earlier the endothelial cells do a lot more than just regulate blood flow with nitric oxide, so damaging them has many other consequences. The vascular endothelium is a monolayer of cells between the vessel lumen and the vascular smooth muscle cells. It is the cardiac muscle that enables the heart to contract and allows for the synchronization of the heartbeat. The endothelium is a thin membrane that coats the inside of blood vessels and the heart. Furthermore, this tissue has an embryonic mesodermal origin. Also, it lines the heart cavities. Damage to the endothelium contributes to the development of atherosclerosis, and hence to possible myocardial infarction and subsequent heart failu … The layer assists in the regulation of mechanisms involved in blood clotting. Far from being inert, it is metabolically active and produces a variety of vasoactive mediators. The tone of the endothelial layer also determines how much work is needed from the heart to pump blood through the body. Branches of the heart’s conduction system are immersed into the subendocardial layer. The endothelium weighs approximately 1 kg in the average patient and covers a total surface area of 4000 to 7000 square meters. Damaged endothelium therefore contributes to hypertension. Damage to the cardiovascular endothelium not only develops with heart disease, but is one of the first steps on the path to heart disease, detectable even before structural changes to the vessel wall are apparent. The endothelium is … The inner layer lines the heart chambers and is made of endothelial cells. It plays a number of roles that are important for the functioning of the cardiovascular system. The heart wall is divided into three layers: epicardium, myocardium, and endocardium. Superiorly, is the second layer: a subendocardial connective tissue which is continuous with the connective tissue of the myocardium. The heart wall is composed of connective tissue, endothelium, and cardiac muscle. The endothelial cells ultimately determine the health of your blood vessels and play a … The endothelial layer has a tone that contributes to the control of blood pressure. 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